Untargeted metabolomics
Sample preparation, GC-MS or LC-MS measurements and data analysis are planned together for comparative metabolic profiling. Feature screening and identification coverage depend on the method.
METABOLOMICS
Metabolomics
Metabolic profiles provide complementary insight into biological responses to physiological and environmental changes. Choose a discovery approach or targeted analysis of selected compounds.
Discuss your project ↗Targeted metabolomics
Define the scope around a target list to identify and quantify selected metabolites. Share your requirements for sulfur, amino acid or energy metabolism studies.
Statistics & biological interpretation
Preprocessing, univariate analysis, PCA, PLS-DA, ROC and pathway analysis are considered according to the study design and suitability of the data. Not every study requires the same analysis package.
RESEARCH FOCUS
Let’s define the focus of your study.
PLAN YOUR STUDY
What will you provide and receive?
Research question
Compare metabolite patterns between groups or investigate selected metabolites.
Before sending samples
Share sample type, collection and storage conditions, group information and study goals.
Deliverables
Feature / metabolite tables, a quality summary, exploratory plots and statistical comparisons as scoped.
Defining the scope
Feature detection, confirmed metabolite identity and absolute quantification are distinct outputs; the reporting level is agreed together.
EXAMPLE ANALYSIS OUTPUT
How similar are the samples?
PCA summarises many metabolite measurements to explore similarities between samples. Each point is one sample.
Possible outputs for your study
Metabolite profile · PCA · Differential analysis
SAMPLE REQUIREMENTS
Sample planning
for metabolomics.
Discuss your requirements for cells, tissue, urine, whole blood, serum and plasma. The amounts below support initial planning and must be confirmed for the analysis before shipping.
| Parameter | Scope |
|---|---|
| Plasma / serum | > 300 µL |
| Urine | > 5 mL |
| Tissue | > 100 mg |
| Cells | > 10⁷ cells |
| Whole blood | Amount and preparation conditions are agreed during consultation. |
HOW WE WORK
A process planned together.
- 01
Share your research
Research question, samples, study groups and replicates.
- 02
Define the scope
Sample preparation, analytical approach and reporting plan.
- 03
Review the results
Agreed analyses and scope of biological interpretation.
LET’S TALK SCIENCE
Let’s start with an email.
Share your research question, analysis or manufacturing requirements. Attach drawings and relevant files to your email.
DIRECT CONTACTbiomicscience@gmail.comÜniversiteler Mah. 1596 Cad. Teknokent Kuluçka Merkez Binası No: 6 C, Unit 11, Çankaya / Ankara, Türkiye